发明名称 |
Method of administration of IGF-I |
摘要 |
A method is disclosed that comprises administering insulin-like growth factor-I (IGF-I) to a mammal so as to sustain its biological activity in the mammal comprising administering a therapeutically effective amount of IGF-I to the mammal to provide an exposure to IGF-I for a period of time that stimulates the maximum biological response in the mammal, then discontinuing said administration for a period of time equal to or less than the time period used for administration, and repeating this pattern of administration and discontinuance of administration for a period as long as necessary to achieve or maintain the desired biological response in the mammal.
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申请公布号 |
US5565428(A) |
申请公布日期 |
1996.10.15 |
申请号 |
US19950447292 |
申请日期 |
1995.05.22 |
申请人 |
GENENTECH, INC.;WASHINGTON UNIVERSITY |
发明人 |
CLARK, ROSS G.;GESUNDHEIT, NEIL;HAMMERMAN, MARC R.;MILLER, STEVEN B. |
分类号 |
A61K38/30;(IPC1-7):A61K38/00;A61K38/27 |
主分类号 |
A61K38/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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