ORAL GASTROINTESTINAL DIAGNOSTIC X-RAY CONTRAST AGENTS IN COMBINATION WITH PHARMACEUTICALLY ACCEPTABLE CLAYS AND SURFACTANTS
摘要
Nanoparticulate crystalline substances formulated with stabilizers and pharmaceutically acceptable clays to enhance contact between the crystalline substances and the gastrointestinal tract. These formulations have improved safety profiles, a low potential for absorption, are not viscous and are not contraindicated for GI perforations or intestinal obstructions. The properties of the surfactant stabilizers are independent of the crystalline drug used and largely determine the extent to which the formulation coats the GI tract.
申请公布号
WO9620734(A3)
申请公布日期
1996.10.10
申请号
WO1995US16446
申请日期
1995.12.04
申请人
EASTMAN KODAK COMPANY;RUDDY, STEPHEN, B.;EICKHOFF, W., MARK;LIVERSIDGE, GARY;COOPER, EUGENE, R.
发明人
RUDDY, STEPHEN, B.;EICKHOFF, W., MARK;LIVERSIDGE, GARY;COOPER, EUGENE, R.