发明名称 |
SUBSTITUTED DIBENZ[a,f]AZULENES AND METHODS OF PREPARATION |
摘要 |
Tetracyclic compounds having structure (1) are described, wherein R1-R10 are as defined. The tetracyclic compounds are capable of potent effects on steroid sensitive tissues and have demonstrated increased uterine weight, antiovolatory effects and potent steroid receptor binding. The compounds have therapeutic utility in reproductive applications such as fertility control, labor induction, ovulation induction and spermatogenesis. Methods for preparing the tetracyclic compounds from substituted indanones are also described.
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申请公布号 |
WO9628403(A1) |
申请公布日期 |
1996.09.19 |
申请号 |
WO1996US02555 |
申请日期 |
1996.03.07 |
申请人 |
ORTHO PHARMACEUTICAL CORPORATION |
发明人 |
DODD, JOHN, E.;DIXON, LISA, A.;BULLINGTON, JAMES, L.;SCHWENDER, CHARLES, F. |
分类号 |
A61K31/015;A61K31/03;A61K31/04;A61K31/085;A61K31/12;A61K31/135;A61K31/165;A61K31/215;A61P13/02;A61P15/00;C07C13/66;C07C23/46;C07C25/22;C07C39/17;C07C43/21;C07C43/215;C07C43/225;C07C43/23;C07C49/755;C07C49/84;C07C65/26;C07C69/00;C07C69/157;C07C69/65;C07C69/734;C07C205/20;C07C205/37;C07C205/42;C07C211/61;C07C217/16;C07C217/24;C07C233/07;C07C233/11;C07C233/15;C07D257/04;C07F9/12;(IPC1-7):C07C13/66;C07C69/16;A61K31/00;C07C49/753 |
主分类号 |
A61K31/015 |
代理机构 |
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代理人 |
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地址 |
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