发明名称 |
IMMUNOTHERAPY FOR RECURRENT HSV INFECTIONS |
摘要 |
Immunotherapy for the treatment of Herpes Simplex Virus eye infections is disclosed. The invention involves a local therapeutic or prophylactic vaccine for the eye, comprising one or more recombinant HSV-1 glycoproteins or proteins, specifically gB and gD, in combination with at least one adjuvant to reduce the incidence of primary HSV-1 infection and/or decrease spontaneous HSV-1 ocular shedding which in turn, controls recurrent corneal disease. |
申请公布号 |
EP0578818(A4) |
申请公布日期 |
1996.05.29 |
申请号 |
EP19930904850 |
申请日期 |
1993.02.03 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
NESBURN, ANTHONY, BART;WECHSLER, STEVEN, LEWIS;GHIASI, HOMAYON |
分类号 |
A61K39/00;A61K39/245;A61K39/39;A61P27/02;A61P31/12;A61P31/22;C07K14/035;C12N7/01;C12N15/866 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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