发明名称 |
Merkede kjemotaktiske peptider for gjenspeiling av infeksjons- og inflamasjonssteder |
摘要 |
<p>The invention relates to a method of detecting a site of infection or inflammation, and a method for treating such infection or inflammation, in an individual by administering to the individual a diagnostically or therapeutically effective amount of detectably labeled, therapeutic, or therapeutically-conjugated, chemotactic peptide that accumulates substantially at the infected or inflamed site, said chemotactic peptide having the general structureX-Y-Leu-Phe-[Z]n-Wwherein: X is an amino protecting group, Y is an amino acid residue, Z is a spacer sequence, n is 0 or 1, and W is a labeling or attachment substituent.</p> |
申请公布号 |
NO961532(D0) |
申请公布日期 |
1996.04.18 |
申请号 |
NO19960001532 |
申请日期 |
1996.04.18 |
申请人 |
GENERAL HOSPITAL CORP, THE;ORTHO PHARMACEUTICAL CORP;JOHNSON MATTHEY INC |
发明人 |
FISCHMAN, ALAN J.;SOLOMON, HOWARD F.;DERIAN, CLAUDIA K.;BRIDGER, GARY JAMES;HIGGINS III, JOHN DAVID;LARSEN, SCOTT KENNETH;HERNANDEZ, PEDRO EMILIO;RUBIN, ROBERT HAROLD;STRAUSS, HARRY WILLIAM;FUCCELLO, ANTHONY JOSEPH;KROON, DANIEL J.;RIEXINGER, DOUGLAS JAMES |
分类号 |
A61K38/00;A61K38/06;A61K49/00;A61K51/00;A61K51/08;A61P29/00;A61P31/00;C07K;C07K5/083;C07K5/103;C07K7/06;(IPC1-7):C07K |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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