发明名称 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
摘要 Esters of acyl L-carnitines of general formula (I) <IMAGE> (I) wherein R is a straight or branched acyl group having 2 to 16 carbon atoms, in particular isobutyryl and isovaleryl; n is an integer comprised between 7 and 15, particularly 10; and, X- is the anion of a pharmacologically acceptable acid are endowed with potent antibacterial activity. Pharmaceutical compositions comprising an ester of formula (I) can be utilized in human therapy and in the veterinary field.
申请公布号 US5498633(A) 申请公布日期 1996.03.12
申请号 US19950408394 申请日期 1995.03.22
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. 发明人 SANTANIELLO, MOSE;TINTI, MARIA O.;MISITI, DOMENICO;FORESTA, PIERO
分类号 A61K31/22;A61P31/04;C07C229/22;(IPC1-7):A61K31/225 主分类号 A61K31/22
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