发明名称 |
Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity |
摘要 |
Esters of acyl L-carnitines of general formula (I) <IMAGE> (I) wherein R is a straight or branched acyl group having 2 to 16 carbon atoms, in particular isobutyryl and isovaleryl; n is an integer comprised between 7 and 15, particularly 10; and, X- is the anion of a pharmacologically acceptable acid are endowed with potent antibacterial activity. Pharmaceutical compositions comprising an ester of formula (I) can be utilized in human therapy and in the veterinary field.
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申请公布号 |
US5498633(A) |
申请公布日期 |
1996.03.12 |
申请号 |
US19950408394 |
申请日期 |
1995.03.22 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
SANTANIELLO, MOSE;TINTI, MARIA O.;MISITI, DOMENICO;FORESTA, PIERO |
分类号 |
A61K31/22;A61P31/04;C07C229/22;(IPC1-7):A61K31/225 |
主分类号 |
A61K31/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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