发明名称 |
AUTOMATED SYSTEM AND METHOD FOR SIMULTANEOUSLY PERFORMING A PLURALITY OF SIGNAL-BASE ASSAYS |
摘要 |
An automated detection system includes a robotic fluid-handling system for performing a plurality of assays; a detection system for imaging the assays as they are performed; and a computer control, data acquisition, and data analysis system for controlling the operation of the fluid-handling and detection system and for collecting and analyzing imaging data. The automated detection system comprises a pipettor for simultaneously distributing a predetermined amount of a liquid and a signal-generating element to each of the plurality of wells; an excitation source for simultaneously exposing the wells to excitation radiation; a detector for simultaneously detecting signal emitted from each of the wells over a period of time comprising a single imager for optically imaging the plurality of wells simultaneously; and computerized controller for simultaneously coordinating the pipettor, the excitation source, and the detector. Further, a method for performing simultaneous assays includes the steps of simultaneously distributing a predetermined amount of a liquid solution to each of a plurality of samples, simultaneously exposing the wells to excitation radiation, simultaneously detecting signals emitted from the wells using a detector comprising a single imaging means, and simultaneously controlling and coordinating the distribution, excitation, and detection using a computerized controller. |
申请公布号 |
WO9605488(A1) |
申请公布日期 |
1996.02.22 |
申请号 |
WO1995US08261 |
申请日期 |
1995.06.30 |
申请人 |
SCIENCE APPLICATIONS INTERNATIONAL CORPORATION;THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCI |
发明人 |
MCNEIL, JOHN, A.;AKONG, MICHAEL, A.;MIERZESKI, DONALD, J.;VELICELEBI, GONUL;KARLTON, DAVID, P. |
分类号 |
G01J3/443;C40B60/14;G01N21/03;G01N21/64;G01N21/78;G01N33/53;G01N35/00;G01N35/02;G01N35/10;(IPC1-7):G01J3/30;C12Q1/02;G01N21/76;G01T1/00;G01J3/42;C12M1/34;G03G21/00 |
主分类号 |
G01J3/443 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|