发明名称 |
USE OF INDOLOCARBAZOLE DERIVATIVES TO TREAT A PATHOLOGICAL CONDITION OF THE PROSTATE |
摘要 |
The invention relates to novel indolocarbazole derivatives, eg. of formula III <CHEM> (wherein: R<1> is selected from the group consisting of halogen, CH2OCONHR<14> and NHCO2R<14>; R<2> is selected from the group consisting of hydrogen and halogen; X is selected from the group consisting of CO2CH3, CH2OH and CONHR<15>; R<14> represents lower alkyl; and R<15> is hydrogen, hydroxy substituted lower alkyl, or aryl; with the proviso that when R<1> = halogen and R<2> = hydrogen, X is neither CO2CH3 nor CH2OH; and with the proviso that when R<1> = R<2> = halogen, X is not CO2CH3; and with the proviso that when R<1> = R<2> = Br, X is not CONHC6H5) which are useful in the treatment of pathological conditions of the prostate gland. |
申请公布号 |
EP0699204(A4) |
申请公布日期 |
1996.01.10 |
申请号 |
EP19940918168 |
申请日期 |
1994.05.27 |
申请人 |
CEPHALON, INC.;KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
DIONNE, CRAIG, A.;CONTRERAS, PATRICIA, C.;MURAKATA, CHIKARA |
分类号 |
A61K31/407;A61K31/5395;A61K31/55;A61K31/553;A61P13/08;A61P35/00;A61P43/00;C07D487/14;C07D498/22;C07H19/04 |
主分类号 |
A61K31/407 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|