| 发明名称 |
RIBOZYMES |
| 摘要 |
Synthetic RNA molecules having highly specific endoribonuclease activity (hereinafter referred to as "ribozymes") are described. The ribozymes comprise a hybridizing region which is complementary in nucleotide sequence to at least part of a target RNA, and a catalytic region which is adapted to cleave the target RNA. Methods for inactivating RNA, and compositions containing ribozymes are also described. |
| 申请公布号 |
HU211891(A9) |
申请公布日期 |
1995.12.28 |
| 申请号 |
HU19950000362P |
申请日期 |
1995.06.22 |
| 申请人 |
GENE SHEARS PTY. LTD. |
发明人 |
GERLACH, WAYNE LYLE;JENNINGS, PHILIP ANTHONY;HASELOFF, JAMES PHILIP;CAMERON, FIONA HELEN |
| 分类号 |
C12N9/22;A01N57/16;A01N63/00;A61K;A61K31/70;A61K31/7105;A61K38/00;A61K39/235;A61K39/285;A61P31/12;C07H;C07H21/02;C12N1/20;C12N5/02;C12N5/10;C12N15/00;C12N15/09;C12N15/113;C12N15/52;C12N15/82;C12P19/34 |
主分类号 |
C12N9/22 |
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