发明名称 |
MATRIX SYSTEM FOR THE TRANSDERMAL DELIVERY OF IBUPROFEN, AND METHOD FOR PREPARING SAME |
摘要 |
A self-adhesive transdermal matrix system for the percutaneous delivery of ibuprofen. The matrix system comprises a carrier and a self-adhesive matrix and is characterised in that said matrix includes (a) 55-75 parts by weight of an adhesive acrylate copolymer with a glass transition temperature of -70 to -10 DEG C, (b) 5-15 parts by weight of a cationic acrylate copolymer with a glass transition temperature of 20-80 DEG C, (c) 5-15 parts by weight of ibuprofen in free acid form, and (d) 10-25 parts by weight of diethyl phthalate. A method for preparing said matrix system is also disclosed. |
申请公布号 |
WO9531193(A1) |
申请公布日期 |
1995.11.23 |
申请号 |
WO1995FR00611 |
申请日期 |
1995.05.10 |
申请人 |
LABORATOIRES D'HYGIENE ET DE DIETETIQUE;SAWAYA, ANTOINE;MATH, MARIE-CHRISTINE |
发明人 |
SAWAYA, ANTOINE;MATH, MARIE-CHRISTINE |
分类号 |
A61K9/70;A61K31/19;A61K31/194;A61K47/32;A61P29/00 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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