发明名称 Process for preparing a physical form of pharmaceutical agent
摘要 A physical form of (_R)-3-methoxy-4-[1-methyl-5-(2-methyl-4,4,4-trifluorobutylcarbamoyl)i ndol-3-ylmethyl]-N-(2-methylphenylsulphonyl)benzamide substantially free of other physical forms, which form is crystalline and has an X-ray powder diffraction pattern with specific peaks at 2 THETA =14.0 DEG , 19.4 DEG , 22.0 DEG , 22.4 DEG and 24.7 DEG , processes for preparing the form and pharmaceutical compositions containing it. The compound is a leukotriene antagonist useful in the treatment of diseases such as asthma.
申请公布号 US5466826(A) 申请公布日期 1995.11.14
申请号 US19940261607 申请日期 1994.06.17
申请人 IMPERIAL CHEMICAL INDUSTRIES, PLC 发明人 CUTHBERT, MURRAY W.
分类号 A61K31/40;A61K9/22;A61K9/48;A61K9/58;A61K31/00;A61K31/18;A61K31/403;A61K31/404;A61P7/04;A61P9/00;A61P11/00;A61P11/06;A61P27/16;A61P37/08;A61P43/00;C07D209/12;C07D209/14;C07D209/24;C07D209/36;(IPC1-7):C07D209/14 主分类号 A61K31/40
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