| 摘要 |
PURPOSE:To obtain a hypotensor containing tea leaf saponins as an active component, exhibiting hypotensive action and low side actions, continuously usable over a long period and useful for the prevention and treatment of hypertension. CONSTITUTION:This hypotensor contains saponins obtained from tea leaf as an active component. The saponin can be prepared e.g. by treating (steamed)tea leaves with an organic solvent such as cyclohexane, extracting the defatted tea leaves with a hydrous lower alcohol such as hydrous methanol, removing catechins from the obtained extract by the treatment with insoluble polyvinyl pyrrolidone, etc., and subjecting the product to chromatography. The daily dose of the hypotensor for adult is preferably 10-2,000mg in terms of saponin in the case of oral administration. |
