发明名称 |
IN UTERO GENE THERAPY FOR FETUSES |
摘要 |
A process for effecting gene therapy in utero in a fetus, which comprises transducing fetal cells in vivo with at least one nucleic acid sequence encoding a therapeutic agent. The fetal cells may be transduced with a viral vector (such as a retroviral vector) which includes the nucleic acid sequence encoding the therapeutic agent. The viral vector may be contained in a viral supernatant which is administered to the fetus, or may be generated by a producer cell line which is administered to the fetus.
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申请公布号 |
WO9515167(A1) |
申请公布日期 |
1995.06.08 |
申请号 |
WO1994US13811 |
申请日期 |
1994.12.02 |
申请人 |
GENETIC THERAPY, INC. |
发明人 |
MOEN, ROBERT, C.;MORRIS, LISA, M.;ZANJANI, ESMAIL, M. |
分类号 |
C12N15/09;A61K31/715;A61K35/76;A61K38/00;A61K38/16;A61K38/43;A61K48/00;A61P43/00;(IPC1-7):A61K31/70 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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