发明名称 |
Expression control sequences |
摘要 |
Expression control sequences are provided for the expression of pro- and eukaryotic proteins. These control sequences are produced by combining promoter sequences having a low signal strength and a high in vivo promoter strength and operator/repressor systems having a high association rate. Expression vectors containing such expression control sequences, microorganisms transformed with such expression vectors and methods for producing pro- and eukaryotic proteins using the expression control sequences, expression vectors and transformed microorganisms are also provided.
|
申请公布号 |
US5362646(A) |
申请公布日期 |
1994.11.08 |
申请号 |
US19910804531 |
申请日期 |
1991.12.11 |
申请人 |
HOFFMAN-LA ROCHE, INC. |
发明人 |
BUJARD, HERMANN;LANZER, MICHAEL |
分类号 |
C12P21/02;C07H21/04;C12N1/20;C12N1/21;C12N15/09;C12N15/70;C12R1/125;C12R1/19;C12R1/42;(IPC1-7):C12N15/00;C12N15/72;C12N15/11 |
主分类号 |
C12P21/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|