METHOD FOR SEPARATING AND RECOVERING 2',3'-DIDEOXYURIDINE

摘要

PURPOSE:To efficiently recover dideoxyuridine (ddU) important as a synthetic raw material for dideoxypurine hopeful as an anti-HIV agent from a solution having completed base exchange reaction with a microorganism or an enzyme. CONSTITUTION:Unreacted ddU is efficiently recovered from a solution having completed exchange reaction of a base comprising ddU and purine bases as a raw material with a microorganism or an enzyme by using a nonpolar porous resin containing divinylbenzene as a constituent element. Dideoxypurines promising as an anti-HIV agent are inexpensively obtained by efficiently recovering ddU.