| 摘要 |
<p>PURPOSE:To provide a new process for easily and site-selectively fluorinating an aromatic ring by simple operation. CONSTITUTION:A fluorinated aromatic compound is synthesized by reacting an N-aryl-N-hydroxyamide with diethylaminosulfur trifluoride (DAST). A fluorinated aromatic compound can be synthesized with simple operation in high yield using an easily handleable commercially available DAST. The process has generality. When a compound having N-hydroxyamide group substituted to an aromatic ring can be synthesized, a fluorine atom can easily be introduced into the aromatic ring to enable the synthesis of a fluorinated aromatic compound which is extremely difficult to synthesize by conventional process.</p> |
