摘要 |
<p>Described are novel quinolinecarboxylic acids of the general formula <CHEM> wherein R<1> is C1-C4 alkyl, R<2> and R<3> each is identically or differently hydrogen or C1-C4 alkyl, R<4> is cyclopropyl, phenyl, halo-phenyl, or thienyl optionally substituted by C1-C4 alkyl or halogen, and R<5> is halogen, or pharmaceutically acceptable salts thereof having a more potent and longer lasting antibacterial activities against G(+) and G(-) bacteria than known analogues.</p> |
申请人 |
SHIONOGI SEIYAKU K.K., OSAKA, JP |
发明人 |
TSUJI, TERUJI, TAKATSUKI-SHI OSAKA, JP;SATO, HISAO, IKOMA-SHI NARA, JP;OKADA, TETSUO, SAKAI-SHI OSAKA, JP |