Process for the preparation of 1,3,3-trimethyl-5-oxo-cyclohexanecarbonitrile.

摘要

To prepare 1,3,3-trimethyl-5-oxocarbonitrile, hydrogen cyanide can successfully be subjected to an addition reaction with isophorone when lithium hydroxide is used in an amount of the order of magnitude of 0.005 to 5 mol % at 100 to 160 DEG C. The product is obtained in high yield and with a considerably higher space-time yield than was possible when other alkali compounds with an alkaline action were used.