摘要 |
PCT No. PCT/EP89/00605 Sec. 371 Date Nov. 15, 1990 Sec. 102(e) Date Nov. 15, 1990 PCT Filed May 30, 1989 PCT Pub. No. WO90/12589 PCT Pub. Date Nov. 1, 1990.Salts of glycosaminoglycans (heparin, its fractions or fragments which are supersulfated, dermatan sulfate, heparan sulfate, and modified heparins) with bases of formula (I), <IMAGE> (I) wherein R1, R2, R3, and R4 represent H, alkyl, or cycloalkyl; R5 and R6 represent H, or alkyl; R7 and R8 represent H or alkyl; n and m are integers from 1-4 and X is -O-CO-O-, which salts have the pharmacological properties of the glycosaminoglycans themselves, and are orally and rectally administrable.
|