发明名称 Glycosaminoglycan salts and pharmaceutical compositions containing them
摘要 PCT No. PCT/EP89/00605 Sec. 371 Date Nov. 15, 1990 Sec. 102(e) Date Nov. 15, 1990 PCT Filed May 30, 1989 PCT Pub. No. WO90/12589 PCT Pub. Date Nov. 1, 1990.Salts of glycosaminoglycans (heparin, its fractions or fragments which are supersulfated, dermatan sulfate, heparan sulfate, and modified heparins) with bases of formula (I), <IMAGE> (I) wherein R1, R2, R3, and R4 represent H, alkyl, or cycloalkyl; R5 and R6 represent H, or alkyl; R7 and R8 represent H or alkyl; n and m are integers from 1-4 and X is -O-CO-O-, which salts have the pharmacological properties of the glycosaminoglycans themselves, and are orally and rectally administrable.
申请公布号 US5264425(A) 申请公布日期 1993.11.23
申请号 US19900623378 申请日期 1990.11.15
申请人 ITALFARMACO S.P.A. 发明人 DAL POZZO, ALMA;ACQUASALIENTE, MAURIZIO;SPORTOLETTI, GIANCARLO;SARRET, MONIQUE;FERRUTI, PAOLO;DE SANTIS, FRANCESCO
分类号 C08B37/10;A61K31/715;A61P3/06;A61P7/02;C07C211/63;C07C219/02;C07C229/06;C07C237/00;C07C237/10;C07C271/06;C07C271/20;C07C275/14;C08B37/00;(IPC1-7):A61K31/725;A61K31/73;C07C69/96 主分类号 C08B37/10
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