Biologically active variant tissue plasminogen activators are disclosed. The disclosure focuses on position 276 variants that exhibit enhanced fibrin specificity.
申请公布号
WO9312225(A1)
申请公布日期
1993.06.24
申请号
WO1992US10677
申请日期
1992.12.14
申请人
GENENTECH, INC.
发明人
HEYNEKER, HERBERT, L.;VEHAR, GORDON, A.;PAONI, NICHOLAS, F.;BENNETT, WILLIAM, F.
