发明名称 |
A METHOD AND COMPOSITION FOR REGULATING SERUM CALCIUM LEVELS OF MAMMALS |
摘要 |
<p>Method for regulating serum calcium levels in mammals by orally administering a composition which includes a polypeptide hormone such as parathyroid hormone (PTH) or calcitonin. The polypeptide hormone is protected from destruction in the digestive tract by encapsulation in liposomes. The liposome preferably includes a cationic amphiphilic agent so that the surface of the liposome has a net positive charge. Agents for enhancing the action of the liposome encapsulated hormones are also disclosed.</p> |
申请公布号 |
EP0233901(B1) |
申请公布日期 |
1993.03.03 |
申请号 |
EP19860904723 |
申请日期 |
1986.07.25 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
HOSTETLER, KARL, Y.;DEFTOS, LEONARD, J. |
分类号 |
A61K38/00;A61K9/10;A61K9/127;A61K38/23;A61K38/29 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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