A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.
申请公布号
WO9220702(A1)
申请公布日期
1992.11.26
申请号
WO1992EP01219
申请日期
1992.05.22
申请人
BUCHARDT, OLE;EGHOLM, MICHAEL;NIELSEN, PETER, EIGIL;BERG, ROLF, HENRIK
发明人
BUCHARDT, OLE;EGHOLM, MICHAEL;NIELSEN, PETER, EIGIL;BERG, ROLF, HENRIK