| 摘要 |
The invention relates to new 1-azabicycloalkane derivatives and their stereoisomers of general formula (I), wherein R<1> représents a phenyl, substituted phenyl, naphthyl or thienyl group, wherein the phenyl group can be substituted by one or several halogen atom(s), methyl, methoxy, methylthio or trifluoromethyl group(s), R<2> represents a hydrogen atom or a C2-5 aliphatic acyl group, R<3> represents a hydrogen atom or a methyl group, n can be zero or one, the dotted line can optionally represent a further C-C bond and the wavy line means that the respective substituent can be bound to the carbon atom in either of the two steric positions, furthermore their pharmaceutically acceptable acid addition salts. Furthermore, the invention relates to a process for preparing the above compounds and pharmaceutical compositions containing the same. The compounds of general formula (I) have valuable therapeutic, mainly antiamnesic, activity. |
