| 摘要 |
<p>Salts of glycosaminoglycans, like heparin and its low molecular weight fractions, glucuronylglycosaminoglycan sulfate, dermatan sulfate and its low molecular weight fractions, prepared by treating said glycosaminoglycans with esters of aminoacids of formula <CHEM> wherein R1 represents hydrogen, straight or branched C1-C6-alkyl, aryl, substituted or unsubstituted arylalkyl, and R2 represents straight or branched C1-C12-alkyl, cycloalkyl, aryl or arylalkyl and pharmaceutical formulations containing them, absorbable by oral administration. These salts show the anticoagulant, antithrombotic and antiatherosclerotic activities typical of the glycosaminoglycans also by oral administration.</p> |
