PEPTIDES WITH A CHARACTERISTIC ANTIGENIC DETERMINANT FOR ALPHA1-MICROGLOBULIN

摘要

A peptide according to the invention is a maximum of 40 amino acids long and contains a sequence which is at least 6 amino acids long from the amino-acid part-sequence between amino acids 144 and 183 of human alpha 1-microglobulin and/or a sequence which is at least 6 amino acids long from the amino-acid part-sequence between amino acids 1 and 20 of human alpha 1-microglobulin. An antibody according to the invention is able to bind specifically both to one of the peptides according to the invention and to human alpha 1-microglobulin. To determine human alpha 1-microglobulin in a sample liquid by an immunoassay, the sample liquid is contacted simultaneously or sequentially with defined amounts of the antibody and peptide components, one of the components being labelled and the determination taking place via this label.