发明名称 VIRUS-GENOMIC INACTIVATOR
摘要 PURPOSE:To obtain a virus.genomic inactivator and carcinogenic promoter inhibitor, containing a specific benzylisoquinoline type alkaloid and an analogue compound thereof as an active ingredient and having extremely strong virus genomic inactivating action. CONSTITUTION:A virus.genomic inactivator and carcinogenic promoter inhibitor containing a compound (e.g. cepharanthine or berbamine) expressed by the formula (R1 to R3 are OH or methoxy; R4 and R5 are H or methyl; R6 and R7 are H, OH or methoxy; X is 0; Y is formyl or R1 and R2 together may be -OCH2O-; X and Y together may be -CH2-) as an active ingredient. The compound expressed by the formula is a bisbenzylisoquinoline type alkaloid present in plants of the family Menispermaceae, etc. The dose of the aforementioned compound is preferably 30-300mg/day in the case of oral administration.
申请公布号 JPH0499723(A) 申请公布日期 1992.03.31
申请号 JP19900215765 申请日期 1990.08.17
申请人 KAKEN SHIYOUYAKU KK 发明人 KOZUKA MUTSUO;FUJIYA MASATOKU;TOKUDA HARUKUNI;KIJIMA TAKAO;AKASU MICHINORI
分类号 C07D217/24;A61K31/47;A61K31/472;A61P31/12;A61P35/00;C07D491/147;C07D491/22 主分类号 C07D217/24
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