发明名称 |
4,4'-(9H-FLUOREN-9-YLIDENEBIS (METHYLENE))BISPYRIMIDINE FOR TREATING NEUROLOGICAL DISORDERS |
摘要 |
A fluorene compound, 4,4'-[9H-fluoren-9-ylidenebis(methylene)]bispyrimidine, or a pharmaceutically acceptable salt thereof is useful in treating various neurological disorders in mammals. This compound has efficacy over a broad dosage range as measured by hypoxia induced cognition impairment and has a wide safety margin as measured by the ratio of cognition to the onset of overt symptoms.
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申请公布号 |
US5087628(A) |
申请公布日期 |
1992.02.11 |
申请号 |
US19900464433 |
申请日期 |
1990.01.12 |
申请人 |
DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
EARL, RICHARD A.;DENOBLE, VICTOR J. |
分类号 |
A61K31/505;A61K31/00;A61P25/28;C07D239/26 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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