发明名称 AMINO ALCOHOLS
摘要 The novel alcohols of the formula <IMAGE> in which R<a> is azido or phthalimido, R<4> is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, and R<7> and R<8> together denote a trimethylene or tetramethylene group which is optionally substituted by hydroxyl, alkoxycarbonylamino or acylamino, or in which a -CH2- group is replaced by -NH-, -N-(alkoxycarbonyl)-, -N(acyl)- or -S-, or to which a cycloalkane ring, an aromatic or a heteroaromatic ring is fused, and R<9> is alkoxycarbonyl, monoalkylcarbamoyl, monoaralkylcarbamoyl, monoarylcarbamoyl or a group of the formula <IMAGE> in which R<10> and R<11> in each case are alkyl, are valuable intermediates, for example in the preparation of amino acid derivatives which can be used for the prophylaxis or treatment of viral infections.
申请公布号 ZA9009744(B) 申请公布日期 1991.08.28
申请号 ZA19900009744 申请日期 1990.12.04
申请人 F. HOFFMANN-LA ROCHE A.G. 发明人 KEVIN EDWARD BURDON PARKES;SALLY REDSHAW;GARETH JOHN THOMAS
分类号 C07D209/48;C07C247/04;C07C247/06;C07C247/10;C07D217/26;C07D303/36;C07D327/10;C07D333/36;C07D401/06;C07D405/06 主分类号 C07D209/48
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