发明名称 |
DNA probe which reveals a hypervariable region on human chromosome 16 |
摘要 |
A DNA probe p79-2-23 is homologous to at least a portion of a hypervariable DNA region located on chromosome 16q22->q24 in the human genome. The DNA region displays a restriction fragment length polymorphism when digested with certain restriction endonucleases. Unrelated individuals display unique fragment patterns on Southern blots probed with p79-2-23. The probe can be used to produce a genetic "fingerprint" for establishing human identity, determining engraftment of bone marrow transplants, determining parentage, and otherwise mapping genes.
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申请公布号 |
US5026837(A) |
申请公布日期 |
1991.06.25 |
申请号 |
US19870103021 |
申请日期 |
1987.09.30 |
申请人 |
THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON HEALTH SCIENCES UNIVERSITY |
发明人 |
LITT, MICHAEL;BUFTON, LINDA L. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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