2-ALKOXY-N-(1-AZABICYCLO(2.2.2) OCT-3-YL) BENZAMIDES AND THIOBENZAMIDES IN A METHOD FOR ALLEVIATING EMESIS CAUSED BY NON-PLATINUM ANTICANCER DRUGS

摘要

2-ALKOXY-N-(1-AZABICYCLO¢2.2.2!OCT-3-YL) BENZAMIDES AND THIOBENZAMIDES IN A METHOD FOR ALLEVIATING EMESIS CAUSED BY NON-PLATINUM ANTICANCER DRUGS A composition for alleviating emesis caused by non-platinum anti-cancer drugs with 2-alkoxy-N-(1-azabicyclo¢2.2.2!oct-3-yl)benzamides and thiobenzamides having the formula wherein X is oxygen or sulfur; R1 is loweralkyl; and R2 is selected from the group consisting of hydrogen, halo, 4,5-benzo, methylsulfonyl, loweralkoxy or Am and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof is disclosed.