发明名称 NAPHTHALENE AND TETRAHYDRONAPHTHALENE SUBSTITUTED GEM- DIPHOSPHONATE
摘要 Compounds of structure (I) <CHEM> where R is hydrogen or C1-4alkyl and q is 0 or 1; R<1> is hydrogen or C1-4alkyl; R<2>, R<3>, R<4> and R<5> are the same or different and are OR<7> in which R<7> is hydrogen or C1-8alkyl; or R<2> and R<3> together and R<4> and R<5> together form a C2-8alkylene dioxy ring; R<6> is hydrogen or C1-4alkyl; m is 0 or 1, and A is S, S(CH2)n, CH=CHCH2, (CH2)n or (CH=CH)p(CH2)tCH= in which n is 1 to 7, p is 0 or 1 and t is 0 to 4, with the proviso that m is 0 only when A is (CH=CH)p(CH2)tCH=, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as antihyperlipidaemic agents.
申请公布号 AU6234590(A) 申请公布日期 1991.03.21
申请号 AU19900062345 申请日期 1990.09.11
申请人 SYMPHAR S.A. 发明人 LAWRENCE IVAN KRUSE;VIRENDRA PREMCHAND SHAH
分类号 C07F9/40;C07F9/6574 主分类号 C07F9/40
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