摘要 |
Compounds of structure (I) <CHEM> where R is hydrogen or C1-4alkyl and q is 0 or 1; R<1> is hydrogen or C1-4alkyl; R<2>, R<3>, R<4> and R<5> are the same or different and are OR<7> in which R<7> is hydrogen or C1-8alkyl; or R<2> and R<3> together and R<4> and R<5> together form a C2-8alkylene dioxy ring; R<6> is hydrogen or C1-4alkyl; m is 0 or 1, and A is S, S(CH2)n, CH=CHCH2, (CH2)n or (CH=CH)p(CH2)tCH= in which n is 1 to 7, p is 0 or 1 and t is 0 to 4, with the proviso that m is 0 only when A is (CH=CH)p(CH2)tCH=, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as antihyperlipidaemic agents. |