A chimaeric protein which presents the CD4 receptor 5 binding site of HIV-1 or HIV-2 is useful as a vaccine against both HIV-1 and HIV-2. Preferably, the CD4 receptor binding site is present at antigenic site 1 of an attenuated type 1 poliovirus.
申请公布号
WO9014842(A1)
申请公布日期
1990.12.13
申请号
WO1990GB00842
申请日期
1990.05.31
申请人
MEDICAL RESEARCH COUNCIL;UNIVERSITY OF READING
发明人
ALMOND, JEFFREY, WILLIAM;EVANS, DAVID, JOHN;MCKEATING, JANE, ALISON;WEISS, ROBIN, ANTHONY
