| 摘要 |
A b s t r a c t Ibuprofen and binders based on cellulose and cellulose derivatives are mixed together, the mixture is moistened with water and extruded, the resulting microspheres are dried, coated with an acrylic resin and mixed with a disintegrant, and the mixture is compressed to form tablets. Optionally, the tablets may be coated with a lacquer layer. The tablets contain at least 600 mg ibuprofen. As a consequence of the high content of active compound and its delayed release in the body, the treatment with ibuprofen can be reduced to a minimum number of intakes and dose units per day. |
