发明名称 Tetrahydrobenz[C,D] indole serotonin agonists.
摘要 <p>This invention provides a 6-substituted-4-(amino or substituted amino)tetrahydrobenz[c,d]indole serotonin agonists of the formula <CHEM> wherein: R<1> is hydrogen, C1-C4 alkyl, allyl or - @-R<4>; R<2> is hydrogen, C1-C4 alkyl or allyl; R<3> is hydrogen, C1-C3 alkoxy, -NR<5>R<6> or C1-C3 alkylthio; R<4> is hydrogen, methyl, ethyl, or vinyl; R<5> and R<6> are independently a C1-C4 alkyl, a C1-C4 alkyl substituted with a phenyl group, or a phenyl group, or R<5> and R<6> together form a C3-C5 heterocyclic ring; R<5> is additionally hydrogen; X is O or S. (</p>
申请公布号 EP0392768(A1) 申请公布日期 1990.10.17
申请号 EP19900303775 申请日期 1990.04.09
申请人 ELI LILLY AND COMPANY 发明人 FLAUGH, MICHAEL EDWARD;FOREMAN, MARK MORTENSEN
分类号 C07D209/58;A61K31/00;A61K31/40;A61K31/403;A61P3/04;A61P13/02;A61P15/00;A61P25/20;A61P25/22;A61P25/24;A61P25/26;C07D209/90 主分类号 C07D209/58
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