发明名称 |
SHELF-STABLE FORMULATION OF GLUCAGON-LIKE PEPTIDE-1 |
摘要 |
Glucagon-like peptide-1 (GLP-1) has been shown to be useful in the treatment of diabetes. The invention encompasses a shelf stable formulation that comprises a therapeutically effective amount of GLP-1, a pharmaceutically acceptable preservative, and a tonicity modifier, and that has a pH between about 8.2 to about 8.8.
|
申请公布号 |
WO0037098(A1) |
申请公布日期 |
2000.06.29 |
申请号 |
WO1999US30395 |
申请日期 |
1999.12.21 |
申请人 |
ELI LILLY AND COMPANY;BRADER, MARK, L.;PEKAR, ALLEN, H. |
发明人 |
BRADER, MARK, L.;PEKAR, ALLEN, H. |
分类号 |
A61K9/08;A61K38/26;A61K38/28;A61K47/10;A61K47/18;A61K47/26;A61P3/10;A61P5/50;C07K14/605;(IPC1-7):A61K38/26 |
主分类号 |
A61K9/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|