摘要 |
A process for synthesizing optically active compounds by asymmetric hydrolysis of a carbinol derivative having a fluorine atom or a fluoroalkyl group using an enzyme as a catalyst, which comprises immobilizing the enzyme on a honeycomb structure of porous ceramics, bringing said carbinol derivative into contact with the immobilized enzyme to conduct asymmetric hydrolysis and, after the reaction has proceeded to a predetermined extent, discontinuing the contact between the enzyme and the carbinol derivatives. |