摘要 |
PURPOSE:To obtain L-threonine useful as an amino acid preparation, etc., in high yield at a low cost, by culturing a specific microorganism belonging to Escherichia genus and separating the objective substance from the cultured product. CONSTITUTION:A microbial strain belonging to Escherichia genus, resistant to rifampicin, lysine, methionine, aspartic acid and homoserine and capable of producing L-threonine [preferably Escherichia coli H-4581 (FERM BP-1411)] is cultured to form and accumulate L-threonine in the cultured product and the objective compound is separated from the product. |