PRODUCTION OF CYANIDE HYDRATASE

摘要

A process for the production of the enzyme cyanide hydratase which comprises aerobically cultivating cells of the fungal strain Fusarium lateritium Nees CMI 300533 and variants and mutants derives therefrom in an aqueous culture containing appropriate nutrients. A method of treating a cyanide-containing material to degrade the cyanide therein using cyanide hydratase produced by the process of the invention and a process for the production of a nitrilase enzyme are also claimed. Fusarium lateritium Nees CMI 300533 is deposited at The Commonwealth Mycological Institute, Kew, Richmond, Surrey, England under the terms of the Budapest Treaty.