摘要 |
Compounds of the formula <CHEM> wherein R1 is cyclopropylmethyl, 2-phenylethyl, aminoalkyl, cycloaminoalkyl, optionally ring-substituted phenoxyalkyl, optionally ring-substituted phenylthioalkyl, optionally ring-substituted phenylsulphinylalkyl, optionally ring-substituted phenylsulphonylalkyl, cycloalkoxyalkyl, optionally ring-substituted phenylalkyl, hydroxyalkyl, alkoxyalkyl or phthalimidoalkyl; R2 is H, alkyl or phenyl; and Y1 is H, Cl, Br, F, MO2 or CF3, can have utility as inhibitors of phospholipase A2 and thus as inhibitors of arachidonic acid cascade biosynthesis. |