发明名称 Integration vectors for the expansion of factor IX in eucaryotic cells, cell lines obtained and method for their preparation.
摘要 <p>A vector for integrating into eucaryotic cells DNA sequences ensuring the expression of factor IX or of a similar protein in the said cells, characterised in that it comprises at least: - a DNA sequence coding for factor IX or the similar protein, - the components ensuring the integration in the form of the multicopy of the said sequence, - the components ensuring, after integration, the expression, in the said cells, of the DNA sequence coding for factor IX or the similar protein.</p>
申请公布号 EP0251874(A1) 申请公布日期 1988.01.07
申请号 EP19870401410 申请日期 1987.06.22
申请人 TRANSGENE S.A. 发明人 DE LA SALLE, HENRI;ELKAIM, RENE
分类号 C07K14/195;C07K14/005;C07K14/745;C12N5/00;C12N5/10;C12N9/64;C12N15/00;C12N15/09;C12P21/00;C12R1/91;(IPC1-7):C12N15/00 主分类号 C07K14/195
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