VITAMIN D-ANALOGVERBINDUNGEN.

摘要

New fluorinated derivatives of vitamin D among which are 24-fluoro- alpha , 25-dihydroxyvitamin D3 and 24-fluoro-1 alpha , 25-dihydroxy-5,6-trans-vitamin D3. The compounds should be a ready substitute for 1 alpha ,25-dihydroxyvitamin D where the need for vitamin D-like activity is indicated but should be more resistant to degradative 24-hydroxylation because of the presence of fluorine as a blocking substituent at C-24.