| 摘要 |
PURPOSE:To obtain an L-amino acid without producing an N-carbamylamino acid as a by-product, by carrying out a reaction at pH of >=neutraility, converting a 5-substituted hydantoin to the L-amino acid and the N- carbamylamino acid and continuing the reaction at pH of <=neutrality. CONSTITUTION:A reaction wherein a 5-substituted hydantoin is treated with an enzymatic system of a bacterium [Arthrobactor (FERM P-7472), Pseudomonas (FERM P-7121), etc.] capable of converting the 5-substituted hydantoin to an L-amino acid is carried out at pH of >=neutrality and the substituted hydrantoin is partially or wholly converted to the L-amino acid and an N-carbamylamino acid. Then, a reaction is continued at pH of >=neutrality to form rapidly the L-amino acid and the N-carbamylamino acid can be converted in high yield to the L-amino acid without accumulating finally the N-carbamylamino acid.
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