发明名称 PYRIMIDONE COMPOUNDS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Novel pyrimidones of the formula I and salts thereof are gastric acid secretion inhibitors and some have other medical utility: <CHEM> wherein R1 represents a hydrogen atom, a C1 to C10 alkyl group, a C1 to C5 alkenyl group, a C1 to C5 alkinyl group, a phenyl group, a cycloalkylmethyl group, an unsubstituted or substituted aralkyl group, or the group <CHEM> wherein A represents a C1 to C5 alkylene group and R3 and R4 are the same or different C1 to C5 alkyl groups or combine to form with the adjacent nitrogen atom a piperidine or pyrrolidine ring; R2 represents a hydrogen atom, a C1 to C5 alkyl group or a trifluoromethyl group: Y represents a heterocyclic group of the formula: <CHEM> wherein R represents a hydrogen atom or a C1 to C5 alkyl group: B represents an oxygen atom or a sulfur atom; m represents zero or an integer of 1 to 3; and n represents an integer of 1 to 3. Methods and novel intermediates for their preparation are disclosed, as well as medicaments containing them and medical treatments using them.
申请公布号 DE3366170(D1) 申请公布日期 1986.10.23
申请号 DE19833366170 申请日期 1983.02.11
申请人 YAMANOUCHI PHARMACEUTICAL CO. LTD. 发明人 YANAGISAWA, ISAO;OHTA, MITSUAKI;TAKAGI, TOKUICHI
分类号 C07D213/55;C07D215/14;C07D231/12;C07D235/16;C07D239/36;C07D277/48;C07D295/096;C07D295/15;C07D317/60;C07D317/62;C07D401/06;C07D403/06;C07D405/06;C07D405/12;C07D405/14;C07D417/12;C07D417/14;(IPC1-7):C07D239/36;A61K31/505;C07C123/00;C07C69/716;C07C69/738 主分类号 C07D213/55
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