摘要 |
Novel carbapenem antibiotics are prepared in which the 2-substituent has the formula <IMAGE> wherein n is 0, 1, 2, 3, m, is 1 or 2, and R is C1-C6 alkyl, allyl, propargyl, carboxymethyl, cyanomethyl or aralkyl wherein the aryl moiety is phenyl or heteroaryl and the alkyl moiety is C1-C6 alkyl, said heterocyclic ring containing the sulfonium group being optionally substituted at a ring carbon atom or atoms by one or two C1-C6 alkyl groups. |