Method for the determination of species in solution with an optical wave-guide

摘要

PCT No. PCT/EP82/00195 Sec. 371 Date May 18, 1983 Sec. 102(e) Date May 18, 1983 PCT Filed Sep. 8, 1982 PCT Pub. No. WO83/01112 PCT Pub. Date Mar. 31, 1983.An analyte in solution is made to react with a spectific reactant coated on the wave-guide thus modifying the optical properties thereof. The index of refraction of the wave-guide material is higher than that of the reaction medium which ensures that a light signal injected into said guide be carried by multiple total reflection, the distance of penetration of the evanescent wave associated with the totally reflected signal being of the same order of magnitude or greater than the thickness of the analyte-reactant product layer.