发明名称 AETHYLENEDIAMINE MONOAMIDE DERIVATIVES
摘要 It has been found, surprisingly, that the ethylenediamine monoamides of the formula <IMAGE> in which R denotes an aromatic 5- or 6-membered heterocyclic radical as defined in Claim 1, as well as their pharmaceutically usable acid addition salts, possess, while being of low toxicity, interesting monoamino oxidase-inhibiting properties and can consequently be used for treating Parkinsonism and conditions which cause depression. With the exception of N-(2-aminoethyl)pyridine-2-carboxamide, all compounds of the formula I are still novel; they can be prepared by known methods.
申请公布号 ZA8506391(B) 申请公布日期 1986.04.30
申请号 ZA19850006391 申请日期 1985.08.22
申请人 F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT 发明人 RENE IMHOF;EMILIO KYBURZ
分类号 C07D213/81;C07D213/84;C07D241/06;C07D261/18;C07D263/34;C07D277/56;C07D307/68;C07D333/38 主分类号 C07D213/81
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