发明名称 Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof
摘要 A series of new 1,5-benzothiazepine analogues are disclosed. These new compounds are represented by the following general formula: <IMAGE> wherein : A is >C=O or >CH2, n is an integer from 1 to 3, B is <IMAGE> wherein R1 represents H, alkyl or acyl group; R2 is <IMAGE> D represents <IMAGE> wherein n' and n'' each represents 1 or 2. R, R', R'' each represents a lower alkyl, Ph represents phenyl group or a substituted phenyl group. The compounds of the present invention are useful as hypertensive agents.
申请公布号 US4584292(A) 申请公布日期 1986.04.22
申请号 US19840662840 申请日期 1984.10.19
申请人 KOTOBUKI SEIYAKU CO., LTD. 发明人 TOMIYAMA, TSUYOSHI
分类号 C07D281/10;(IPC1-7):A61K31/55;A61K31/44;C07D285/36;C07D417/06 主分类号 C07D281/10
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