发明名称 Water soluble derivatives of cephalex and process for their preparation
摘要 The water soluble derivatives of cephalexin, having general formula: <IMAGE> wherein X represents an alkali metal or the organic nitrogen containing cation of a basic aminoacid, combine the typical antibiotic action of cephalexin with the water solubility and form essentially neutral, aqueous solutions. The process for the preparation of the above derivatives comprises a first step in which the methylol derivative of cephalexin is prepared and a second step in which the treatment with a suitable base is carried out.
申请公布号 US4471115(A) 申请公布日期 1984.09.11
申请号 US19820452159 申请日期 1982.12.22
申请人 NEOPHARMED S.P.A. 发明人 REINER, ALBERTO
分类号 A61K;A61K9/08;A61K31/545;A61K31/546;A61P31/04;C07D;C07D501/00;C07D501/04;C07D501/22;(IPC1-7):C07D501/04 主分类号 A61K
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