Dentrifice compositions.

摘要

Antiplaque dentifrices containing as the antiplaque ingredient the saccharin salt of an amino or quaternary ammonium antimicrobial agent, particularly chlorhexidine saccharin salt or octenidine saccharin salt, and the method of inhibiting, reducing and preventing dental plaque therewith are disclosed. Novel bis[4-(substituted-amino)-1-pyridinium]alkane saccharin salts are prepared from corresponding relatively soluble salts and saccharin or a soluble salt of saccharin and are useful as antimicrobial agents.