1-(3,4-DIHYDROXYPHENYL)ALKANE

摘要

NEW MATERIAL:A 1-(3,4-hydroxyphenyl)alkane expressed by formula I (m is an integer 0-8; Y is hydroxymethylene, lower alkoxymethylene or carbonyl; R is alkyl or cycloalkyl, provided that Y is alkoxymethylene when m is 2). EXAMPLE:1-(3,4-Dihydroxyphenyl)-2-decanol. USE:An antiallergic agent, preventing and treating agent for ischemic diseases and inflammations caused by slow-reaction substances of anaphylaxis (SRS-A), etc. and intermediates for medicines. PREPARATION:For example, a 1-(3,4-disubstituted phenyl)alkane expressed by formula II1 (m' is an integer 0-6; R' is a protecting group of OH; Y' is Y) or a 1-(3,4-disubstituted phenyl)alkene expressed by formula II2 is reduced to afford the aimed compound expressed by formula I .